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Reviews and clarifies the determinants that affect, and those that can be manipulated to control, the uptake and delivery of drugs and xenobiotics to the lymph. Addressed to pharmaceutical scientists interested either in designing new agents for delivery to the lymph, or in altering the delivery of current therapeutic agents through formulation or prodrug approaches. The focus is on drugs administered orally, so much attention is given to intestinal/lymphatic interactions. Annotation copyright Book News, Inc. Portland, Or.


Book Description
Lymphatic Transport of Drugs provides a thorough review of the determinants that affect the uptake and delivery of drugs and xenobiotics to the lymphatics. Factors affecting the transport and delivery of lipophilic drugs through the lymph after oral administration, lymphatic transport of polar drugs and macromolecules after gastrointestinal dosing, transport of drugs into the lymph after parenteral administration, and particulate drug delivery systems are among the topics examined in this volume. Lymphatic Transport of Drugs is primarily intended for pharmaceutical scientists who are attempting to alter the delivery of current therapeutic agents through formulation of prodrugs, as well as for researchers designing new drugs for lymph delivery.

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