From Book News, Inc.
Provides a comprehensive, current overview of solid organ transplant rejection in 24 contributed chapters, considering mechanisms of rejection; pathology of rejection and allied conditions; clinical diagnosis; molecular biology in diagnosis of rejection; and pathologic effects of antirejection agents. Both acute and chronic rejection in all types of solid organ allografts are considered. Advances in such areas as new immunosuppressive protocols, induction of tolerance, and xenografting are discussed only briefly, emphasis being given rather to the general background and context into which these and other breakthroughs can be assimilated in the future. Chapter references are particularly extensive. Illustrated in b&w throughout, with a six-page section of color plates. Annotation c. by Book News, Inc., Portland, Or.


Book Description
This state-of-the-art reference provides a valuable overview of the basic mechanisms, molecular biology, histopathology, and clinical diagnosis of solid organ transplant rejection and related conditions--offering comprehensive coverage of both acute and chronic rejection in all types of solid organ allografts.

ANNOTATION

The book contains predominantly black-and-white illustrations, with some color illustrations.

FROM THE CRITICS

Doody's Health Sciences Book Review Journal

...The most up-to-date treatment of the subject of solid organ transplantation....Transplant physicians, surgeons, and pathologists should own or have ready access to this book.

Daniel C. Brennan

This book details the contemporary experience of solid organ transplantation and rejection. Its purpose is broader than merely to describe the histological findings or rejection that occurs in the various organs. This book also considers the basic mechanisms of rejection as well as molecular biological approaches for investigation of these mechanisms and use of these molecular biological approaches for the diagnosis of rejection. This book confronts the issues of clinical diagnosis and treatment of acute rejection as well as the complex nature of chronic rejection. There is also a chapter on new immunosuppressive medications. Different from some recent books on transplant rejection, this book covers only solid organ transplantation and does not address bone marrow transplantation. The book is intended for a wide range of professionals involved in the care of solid organ transplantation and generally satisfies this intent. The editors and authors are credible. The black-and-white photomicrographs of x-rays, echocardiograms, and histology are generally adequate if one has familiarity with the organ system in question. However, I found the black-and-white histological photomicrographs of unfamiliar organ systems to be less useful. However, the text description was usually written in such a way to overcome this deficiency. The color photomicrographs are limited in number and clarity of their presentation, as compared with more recently published books on transplant pathology. The most unique feature of this book is that it is the most up-to-date treatment of the subject of solid organ transplantation. It is very useful. It functions not only as a histological reference but also asa reference for the mechanisms of rejection, clinical diagnosis of rejection, and as an introduction to the use of molecular biology for the diagnosis of rejection. Transplant physicians, surgeons, and pathologists should own or have ready access to this book.

Doody Review Services

Reviewer: Daniel C Brennan, MD (Washington University School of Medicine)Description: This book details the contemporary experience of solid organ transplantation and rejection. Purpose: Its purpose is broader than merely to describe the histological findings or rejection that occurs in the various organs. This book also considers the basic mechanisms of rejection as well as molecular biological approaches for investigation of these mechanisms and use of these molecular biological approaches for the diagnosis of rejection. This book confronts the issues of clinical diagnosis and treatment of acute rejection as well as the complex nature of chronic rejection. There is also a chapter on new immunosuppressive medications. Different from some recent books on transplant rejection, this book covers only solid organ transplantation and does not address bone marrow transplantation. Audience: The book is intended for a wide range of professionals involved in the care of solid organ transplantation and generally satisfies this intent. The editors and authors are credible. Features: The black-and-white photomicrographs of x-rays, echocardiograms, and histology are generally adequate if one has familiarity with the organ system in question. However, I found the black-and-white histological photomicrographs of unfamiliar organ systems to be less useful. However, the text description was usually written in such a way to overcome this deficiency. The color photomicrographs are limited in number and clarity of their presentation, as compared with more recently published books on transplant pathology. Assessment: The most unique feature of this book is that it is the most up-to-date treatment of the subject of solid organ transplantation. It is very useful. It functions not only as a histological reference but also as a reference for the mechanisms of rejection, clinical diagnosis of rejection, and as an introduction to the use of molecular biology for the diagnosis of rejection. Transplant physicians, surgeons, and pathologists should own or have ready access to this book.

Booknews

Provides a comprehensive, current overview of solid organ transplant rejection in 24 contributed chapters, considering mechanisms of rejection; pathology of rejection and allied conditions; clinical diagnosis; molecular biology in diagnosis of rejection; and pathologic effects of antirejection agents. Both acute and chronic rejection in all types of solid organ allografts are considered. Advances in such areas as new immunosuppressive protocols, induction of tolerance, and xenografting are discussed only briefly, emphasis being given rather to the general background and context into which these and other breakthroughs can be assimilated in the future. Chapter references are particularly extensive. Illustrated in b&w throughout, with a six-page section of color plates. Annotation c. Book News, Inc., Portland, OR (booknews.com)

RATING

3 Stars from Doody

ACCREDITATION

Solez, Kim, MD (Univ of Alberta); Racusen, Lorraine C., MD (Johns Hopkins Univ); Billingham, Margaret E., MB, BS, FRCPath (Stanford Univ)