From Publishers Weekly
Temporal lobe epilepsy (TLE) is the most widespread form of epilepsy among adults, yet TLE seizures are not easily recognized, unlike the far better known convulsions of grand mal epilepsy. In this major study, freelance journalist LaPlante, who interviewed scores of patients and doctors, explores a disease that may affect between one and two million Americans. During a TLE seizure, a person is overcome by powerful emotions, hallucinations, or vivid flashbacks. Some TLE sufferers perform automatic or violent acts; others exhibit hyper-religiosity or altered sexuality. LaPlante reviews the ordeals of Dostoevsky, van Gogh, Lewis Carroll and other luminaries thought to have suffered TLE. She also graphically profies three ordinary TLE patients--Charlie, a lawyer minimally affected by the disease; Jill, a personnel director whose confidence has been shattered by her seizures; and Gloria, a retired hairdresser. If TLE often gets misdiagnosed as schizophrenia or mood disorder, as LaPlante suggests, the implications for psychiatry are staggering. Copyright 1993 Reed Business Information, Inc.


From Library Journal
The many readers who were intrigued by Oliver Sacks's The Man Who Mistook His Wife for a Hat ( LJ 2/15/86) will welcome LaPlante's book. More common yet less familiar than the physical manifestations of grand mal epilepsy, temporal lobe epilepsy (TLE) is a response to abnormal electrical activity in the parts of the brain controlling feeling and memory. In TLE seizures, a patient experiences uncontrollable, intense emotions, sensory hallucinations, and vivid memories. Unlike grand mal epilepsy, the intervals between seizures are often marked by a common pattern of personality changes, typically including compulsive writing or drawing and hyper-religiosity. LaPlante interweaves the stories of three contemporary sufferers with accounts of famous people who probably had the disease, including Vincent Van Gogh, Soren Kierkegaard, and Lewis Carroll. Does the development of anticonvulsant drugs preclude another Alice in Wonderland ? A thoughtful final chapter examines TLE's conjunction of personality and physiology and its impact on our concepts of personhood, creativity, and free will. Highly recommended for all libraries.- Kathy Arsenault, Univ. of South Florida-St. Petersburg Lib.Copyright 1993 Reed Business Information, Inc.


From Kirkus Reviews
What did Moses, Van Gogh, Lewis Carroll, and Dostoyevsky have in common? Quite possibly temporal lobe epilepsy, according to this fascinating report by freelance writer LaPlante (The Atlantic, Yankee, etc.). Temporal lobe epilepsy (TLE) is the most common form of epilepsy among adults. Its seizures bring hallucinations, dreamy states, bizarre feelings, and involuntary actions resembling the symptoms of psychiatric disease, and the personalities of its sufferers are frequently marked by an intense interest in religion and morality, a compulsion to write or draw, altered sexuality, aggression, and hypersociability. LaPlante traces the history of the disorder from its early definition by a 19th- century English neurologist to present-day efforts to understand and treat it with drugs and/or surgery. She chronicles its effects on three pseudonymous patients: Charlie, a lawyer whose first seizure occurred when he was in his 50s; Jill, a personnel director in her 30s whose life has been drastically affected by the onset of TLE; and Gloria, a middle-aged woman who's suffered from TLE all her life and had been treated for a myriad of psychiatric disorders prior to the diagnosis of TLE at age 37. What makes TLE especially intriguing are the clues it offers to biological bases of creativity, spirituality, and--on a less positive note--violence. Moreover, because TLE crosses the boundaries between psychiatry and neurology, research on it holds promise for a better understanding of the physiological causes of mental illness. LaPlante's descriptions of the human brain are wonderfully concrete, her historical research is well presented, and her empathy for TLE's victims is clear. A well-done study. (Line drawings--not seen) -- Copyright ©1993, Kirkus Associates, LP. All rights reserved.


From Book News, Inc.
The author draws together a number of case studies and interweaves current thinking about a disorder that sometimes results in disability, sometimes in genius, and which has been shown to involve the personality although exact interrelationships are unclear. The material has been well-researched, but the dramatized case studies cloud rather than clarify the presentation. Annotation copyright Book News, Inc. Portland, Or.


Publishers Weekly
"A major study...the implications for psychiatry are staggering."


Kirkus Review
"LaPlante's descriptions of the human brain are wonderfully concrete, and her empathy for epilepsy's victims is clear."


Book Description
"Fascinating account of medical research...LaPlante shows how a brain scar may cause bizarre aggressive or sexual behavior-and works of profound creative imagination."

—Howard Gardner

"Readers intrigued by Oliver Sacks' Man Who Mistook His Wife For A Hat will welcome LaPlante's book...Thoughtful...Highly recommended."

—Library Journal

"LaPlante's descriptions of the human brain are wonderfully concrete, and her empathy for epilepsy's victims is clear."

—Kirkus Review


About the Author
Eve LaPlante has degrees from Princeton and Harvard. She has written for The Atlantic Monthly, The New York Times, Ladies' Home Journal, Working Woman, Parents, Country Living, and many other publications. She is working on a book about children of divorce.

FROM THE PUBLISHER

Its symptoms are varied, involving an extraordinary range of behaviors: hallucinations, flashbacks, intense anger and fear, heightened religious feelings, changes in sexual interest, a compulsion to write or draw. Temporal lobe epilepsy (TLE), a condition that affects more than a million Americans, is one of the most common neurological disorders, yet one of the most remarkable. In its depths may lie not only a hidden source of creativity, but clues to one of the greatest scientific riddles of our time - the link between body and mind. In Seized, journalist Eve LaPlante has written a compelling chronicle of the lives of three ordinary people with this extraordinary disease: a corporate executive, a small-town attorney, and a former prison inmate and mental patient. Although TLE is the most common form of epilepsy among adults, it remains a challenge to diagnose and treat because of its manifold guises and degrees of severity. The stories of these patients show the amazing array of TLE's effects, both positive and negative, and illustrate how people manage to cope with the disorder by adapting in desperate or constructive ways. Interwoven with these narratives are accounts of the pioneering efforts by doctors to find a cure, from early, often harmful interventions - such as castration and psychosurgery - to today's hopeful drug therapies and neurosurgery. As the book reveals, what continues to make TLE a promising subject for research, as well as fascinating medical mystery, is its suggestive link to creativity. Moses, Saint Paul, Dostoevsky, Flaubert, van Gogh, and Lewis Carroll are only a few of the prominent figures portrayed in Seized who are thought to have had the disease, which may account for distinctive features in their lives and work. Dostoevsky, for example, described in fiction the ecstasy that can precede a TLE seizure, while van Gogh's phenomenal artistic output in the late 1880s is also characteristic of TLE. Rare among diseases, TLE crosses the

FROM THE CRITICS

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