Review
"The introductory chapter provides an excellent overview of the implications of advances in immunology for understanding the pathogenesis and treatment of rheumatic diseases...The list of authors includes important names in the field...an excellent resource in a single volume for those with clinical or scientific interests in the rheumatic diseases. For the clinician it provides a starting point for understanding the rationale behind current therapeutic approaches in rheumatology and will foster a better understanding of new research in immunology and its application to the treatment of the rheumatic diseases." Journal of Rheumatology

"...a good read..." Rheumatology

"This is an outstanding contribution. The frequent attempts to show the relevance of immunological principles to disease distinguish this volume from basic immunology and clinical rheumatology books. Indeed, this is an outstanding bridge between perspectives usually provided in both types of books." Doody's Health Sciences Book Review Journal


Book Description
This authoritative volume provides a wide-ranging account of the immunological mechanisms that underlie many rheumatic diseases. Advances in our understanding of the immunopathology of diseases such as rheumatoid arthritis, ankylosing spondylitis and SLE, are paving the way for the development of effective and rational new therapies. This exciting prospect is an important influence for ground-breaking research into these diseases and the investigation of new therapeutic options. As the first book to focus exclusively on this burgeoning area of clinical research, this is an invaluable and current resource for all rheumatologists, clinical immunologists, and those seeking to develop effective new therapies to combat rheumatic diseases.


Book Info
Univ. of Cambridge, UK. Provides an account of the immunological mechanisms that underlie many rheumatic diseases. For rheumatologists, clinical immunologists, and those seeking new therapies to combat rheumatic diseases. Halftone illustrations. Referenced. DNLM: Rheumatic Diseases.

ANNOTATION

The book contains black-and-white illustrations.

FROM THE PUBLISHER

This authoritative volume provides a wide-ranging account of the immunological mechanisms that underlie many rheumatic diseases. Advances in our understanding of the immunopathology of diseases such as rheumatoid arthritis, ankylosing spondylitis and SLE, are paving the way for the development of effective and rational new therapies. This exciting prospect is an important influence for ground-breaking research into these diseases and the investigation of new therapeutic options. As the first book to focus exclusively on this burgeoning area of clinical research, this is an invaluable and current resource for all rheumatologists, clinical immunologists, and those seeking to develop effective new therapies to combat rheumatic diseases.

FROM THE CRITICS

Wayne M. Yokoyama

This is a review of basic immunology with respect to autoimmune diseases. Throughout the text, major conceptual points are discussed with respect to mechanisms potentially involved in the pathogenesis of rheumatic diseases. This volume provides an overview of immunolgical principles and mechanisms that are relevant to inflammatory and autoimmune rheumatic diseases. Particularly with the current rapid translation of basic immunology to the rheumatology clinic, these goals are worthy. This book is intended for ""rheumatologists, clinical immunologists, and those seeking to develop effective new therapies to combat rheumatic diseases."" Those currently involved in clinical trials, as well as practitioners using the latest agents (i.e., TNF-a blockade), will benefit from this book. The contributors are largely European and they provide an authoritative perspective on complex topics. Most of the major areas of immunology are discussed within the context of disease pathogenesis. The frequent references to specific disorders when covering basic immunological topics highlight this book. Interestingly, however, the book is ""lymphocyte-centric."" Inflammation is only superficially covered and there is no mention of COX-2. Perhaps the next edition will include a chapter on other immune calls (neutrophils, macrophages) and inflammatory mediators. This is an outstanding contribution. The frequent attempts to show the relevance of immunological principles to disease distinguish this volume from basic immunology and clinical rheumatology books. Indeed, this is an outstanding bridge between perspectives usually provided in both types of books.

Doody Review Services

Reviewer: Wayne M. Yokoyama, MD (Washington University Medical Center)Description: This is a review of basic immunology with respect to autoimmune diseases. Throughout the text, major conceptual points are discussed with respect to mechanisms potentially involved in the pathogenesis of rheumatic diseases. Purpose: This volume provides an overview of immunolgical principles and mechanisms that are relevant to inflammatory and autoimmune rheumatic diseases. Particularly with the current rapid translation of basic immunology to the rheumatology clinic, these goals are worthy. Audience: This book is intended for "rheumatologists, clinical immunologists, and those seeking to develop effective new therapies to combat rheumatic diseases." Those currently involved in clinical trials, as well as practitioners using the latest agents (i.e., TNF-a blockade), will benefit from this book. The contributors are largely European and they provide an authoritative perspective on complex topics. Features: Most of the major areas of immunology are discussed within the context of disease pathogenesis. The frequent references to specific disorders when covering basic immunological topics highlight this book. Interestingly, however, the book is "lymphocyte-centric." Inflammation is only superficially covered and there is no mention of COX-2. Perhaps the next edition will include a chapter on other immune calls (neutrophils, macrophages) and inflammatory mediators. Assessment: This is an outstanding contribution. The frequent attempts to show the relevance of immunological principles to disease distinguish this volume from basic immunology and clinical rheumatology books. Indeed, this is an outstanding bridge between perspectives usually provided in both types of books.

RATING

3 Stars from Doody

ACCREDITATION